Noun

1. Any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease
2. A decrease in size of an organ caused by disease or disuse

Verb

1. Spend thoughtlessly; throw away
2. Use inefficiently or inappropriately
3. Get rid of
4. Run off as waste
5. Get rid of (someone who may be a threat) by killing
6. Spend extravagantly
7. Lose vigor, health, or flesh, as through grief
8. Cause to grow thin or weak
9. Cause extensive destruction or ruin utterly
10. Become physically weaker